Motif ID: TAL1_TCF{3,4,12}.p2

Z-value: 0.393


Transcription factors associated with TAL1_TCF{3,4,12}.p2:

Gene SymbolEntrez IDGene Name
TAL1 6886 T-cell acute lymphocytic leukemia 1
TCF12 6938 transcription factor 12
TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF3chr19_-_1650246-0.677.2e-02Click!
TCF4chr18_-_53257033-0.383.5e-01Click!
TAL1chr1_-_47695442-0.294.9e-01Click!
TCF12chr15_+_57511616-0.078.8e-01Click!


Activity profile for motif TAL1_TCF{3,4,12}.p2.

activity profile for motif TAL1_TCF{3,4,12}.p2


Sorted Z-values histogram for motif TAL1_TCF{3,4,12}.p2

Sorted Z-values for motif TAL1_TCF{3,4,12}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TAL1_TCF{3,4,12}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_158300517 0.402 NM_004288
CYTIP
cytohesin 1 interacting protein
chr2_+_152214105 0.397 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_33359607 0.237 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr6_-_163148716 0.199 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr6_+_86159738 0.181 NT5E
5'-nucleotidase, ecto (CD73)
chr3_-_195310985 0.161 NM_001647
APOD
apolipoprotein D
chr10_-_73848530 0.141 NM_001244950
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_73848766 0.133 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr16_+_2587989 0.125 PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_+_189839078 0.125 NM_000090
COL3A1
collagen, type III, alpha 1
chr12_+_75874512 0.123 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr3_-_149095517 0.119 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr2_+_189839132 0.117 COL3A1
collagen, type III, alpha 1
chr16_+_2588000 0.114 PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_-_71746966 0.110


chr16_+_2587951 0.107 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr1_-_33813261 0.104


chr22_+_31003069 0.102 NM_000355
NM_001184726
TCN2

transcobalamin II

chr19_-_39368889 0.100 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr3_-_195310770 0.099 APOD
apolipoprotein D
chr10_-_14050453 0.097 FRMD4A
FERM domain containing 4A
chr1_-_150738232 0.096 CTSS
cathepsin S
chr4_+_114214102 0.092 ANK2
ankyrin 2, neuronal
chrX_-_46618471 0.087 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr2_+_191301020 0.085 MFSD6
major facilitator superfamily domain containing 6
chr3_+_10068123 0.082 FANCD2
Fanconi anemia, complementation group D2
chr2_-_96956458 0.082 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr5_+_173472737 0.081 HMP19
HMP19 protein
chrX_-_34675366 0.080 NM_031442
TMEM47
transmembrane protein 47
chr2_+_177016337 0.080


chrX_-_46618596 0.079 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr17_-_47286742 0.076 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr1_-_220219853 0.075 EPRS
glutamyl-prolyl-tRNA synthetase
chr7_-_92855780 0.074 NM_001039372
HEPACAM2
HEPACAM family member 2
chr20_+_60174816 0.074 NM_001252339
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr9_+_72658496 0.074 NM_153267
MAMDC2
MAM domain containing 2
chr4_+_55095263 0.073 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_108994366 0.072 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr17_+_41003184 0.071 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr9_-_8733893 0.071 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chrX_+_85517970 0.067 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr16_-_69385656 0.067 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr2_+_189839113 0.066 COL3A1
collagen, type III, alpha 1
chr10_-_75457553 0.066 NM_001144000
AGAP5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
chr9_-_104357202 0.063 NM_147180
PPP3R2
protein phosphatase 3, regulatory subunit B, beta
chr1_+_215178884 0.062 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr6_-_41703938 0.061 NM_001167827
TFEB
transcription factor EB
chr1_-_23521221 0.061 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr7_+_76139744 0.060 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr7_+_90893678 0.059 FZD1
frizzled family receptor 1
chr2_-_154335181 0.058 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_150738255 0.057 CTSS
cathepsin S
chr7_+_155437325 0.055 RBM33
RNA binding motif protein 33
chr22_+_40322609 0.054 GRAP2
GRB2-related adaptor protein 2
chr5_+_139876504 0.053 ANKHD1
ankyrin repeat and KH domain containing 1
chrX_+_69509878 0.052 NM_012310
KIF4A
kinesin family member 4A
chr3_+_133494275 0.051 TF
transferrin
chr7_+_155437143 0.050 RBM33
RNA binding motif protein 33
chr19_-_12997956 0.050 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr7_+_93551015 0.050 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr5_-_142783975 0.050 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_233877901 0.049 NGEF
neuronal guanine nucleotide exchange factor
chr12_-_48119224 0.049 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr16_+_68279297 0.049 PLA2G15
phospholipase A2, group XV
chr7_-_155437056 0.049


chr1_-_226076766 0.049 NM_020997
LEFTY1
left-right determination factor 1
chr4_+_88742549 0.048 NM_001184694
MEPE
matrix extracellular phosphoglycoprotein
chr2_-_163099877 0.048 NM_004460
FAP
fibroblast activation protein, alpha
chr17_-_49124128 0.048 NM_001251971
SPAG9
sperm associated antigen 9
chr1_-_220219874 0.047 NM_004446
EPRS
glutamyl-prolyl-tRNA synthetase
chr12_+_1738411 0.047 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr1_-_17307107 0.046 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr7_+_80275634 0.045 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr1_-_220219833 0.045 EPRS
glutamyl-prolyl-tRNA synthetase
chr3_+_10068097 0.042 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr6_-_56407681 0.041


chr2_-_55277698 0.041 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr6_-_30080866 0.040 NM_007028
TRIM31
tripartite motif containing 31
chr2_-_55277653 0.040 RTN4
reticulon 4
chr12_+_62954275 0.040 MON2
MON2 homolog (S. cerevisiae)
chr10_-_69991854 0.040 NM_145178
ATOH7
atonal homolog 7 (Drosophila)
chr17_-_67311773 0.039 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr7_+_127233688 0.039 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr7_+_90893735 0.038 NM_003505
FZD1
frizzled family receptor 1
chr16_+_68279206 0.038 NM_012320
PLA2G15
phospholipase A2, group XV
chr2_+_177016112 0.038 NM_014621
HOXD4
homeobox D4
chr20_-_39766522 0.038


chrX_+_128872924 0.038 NM_003399
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr3_+_141043054 0.037 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr11_-_75141517 0.037 NM_001039548
KLHL35
kelch-like 35 (Drosophila)
chr2_-_55277672 0.037 RTN4
reticulon 4
chr11_-_58611979 0.037 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr5_+_38403633 0.036 NM_182798
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr2_-_55277620 0.035 RTN4
reticulon 4
chr1_-_183622447 0.035 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chrX_-_19688991 0.035 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr16_+_53133063 0.035 CHD9
chromodomain helicase DNA binding protein 9
chr2_-_55277592 0.034 RTN4
reticulon 4
chr8_+_9413390 0.033 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_+_163149001 0.033 NM_001080379
PACRG
PARK2 co-regulated
chr10_-_50122279 0.033 NM_001006939
LRRC18
leucine rich repeat containing 18
chr6_-_163148798 0.033 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr8_+_54764367 0.032 NM_170587
RGS20
regulator of G-protein signaling 20
chr17_+_14204326 0.032 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_-_41122025 0.032 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr2_-_233877920 0.032 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr5_-_176326314 0.032 NM_002115
HK3
hexokinase 3 (white cell)
chrX_+_38211735 0.031 NM_000531
OTC
ornithine carbamoyltransferase
chr3_-_10332408 0.031 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr16_+_2588021 0.031 PDPK1
3-phosphoinositide dependent protein kinase-1
chr5_+_53751430 0.031 NM_006308
HSPB3
heat shock 27kDa protein 3
chr1_-_54199876 0.030 NM_147193
GLIS1
GLIS family zinc finger 1
chr1_-_232651227 0.029 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_+_36772696 0.029 NM_024676
SH3D21
SH3 domain containing 21
chr11_-_116663106 0.029 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr1_-_204165542 0.029 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr9_+_72658735 0.028 MAMDC2
MAM domain containing 2
chrX_+_152082985 0.027 NM_001178106
NM_001178107
NM_001178108
NM_001178109
NM_001178110
NM_007150
ZNF185





zinc finger protein 185 (LIM domain)





chr2_-_55277459 0.027 RTN4
reticulon 4
chr19_+_51760963 0.027 NM_173635
C19orf75
chromosome 19 open reading frame 75
chr7_+_149473130 0.026 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr12_-_62586547 0.026 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr14_+_101295409 0.025 MEG3
maternally expressed 3 (non-protein coding)
chr3_+_122296432 0.025 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr22_+_31478845 0.025 NM_001207017
SMTN
smoothelin
chr2_-_158731622 0.025 NM_001105
ACVR1
activin A receptor, type I
chr19_+_46195740 0.024 NM_001163377
NM_017659
QPCTL

glutaminyl-peptide cyclotransferase-like

chr6_-_128841432 0.024 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr19_-_14889347 0.024 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr19_-_51472816 0.024 NM_002774
KLK6
kallikrein-related peptidase 6
chr5_+_155754172 0.023 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr15_+_91447419 0.023 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr3_+_10068139 0.023 FANCD2
Fanconi anemia, complementation group D2
chr1_+_159409511 0.023 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr10_-_98321823 0.022 TM9SF3
transmembrane 9 superfamily member 3
chr9_-_14722669 0.022 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr21_+_39628869 0.022 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_+_125953746 0.021 NM_001122716
CXorf64
chromosome X open reading frame 64
chr2_+_61404549 0.021 NM_152392
AHSA2
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr4_+_15376174 0.021 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_-_152146373 0.020 NM_004688
NMI
N-myc (and STAT) interactor
chr5_+_154092461 0.020 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr8_+_9413439 0.020 NM_003747
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr14_-_24423329 0.020 C14orf167
chromosome 14 open reading frame 167
chr11_+_5410606 0.020 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr11_-_2182408 0.020 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough
chr2_+_187464931 0.019 NM_001144999
ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr7_-_76038894 0.019 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr3_+_9958757 0.019 NM_001203263
NM_001203264
NM_001203265
NM_032732
NM_153460
NM_153461
IL17RC





interleukin 17 receptor C





chr10_+_81073763 0.019 ZMIZ1
zinc finger, MIZ-type containing 1
chr15_-_31453382 0.019 NM_001252020
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr16_+_57728711 0.019 NM_032269
CCDC135
coiled-coil domain containing 135
chr3_-_178984789 0.019 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr2_-_55199894 0.018


chr11_+_61891414 0.018 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chrX_+_135067573 0.018 NM_001177651
NM_001042537
NM_006359
SLC9A6


solute carrier family 9 (sodium/hydrogen exchanger), member 6


chr16_-_81253974 0.018 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chrX_-_48056198 0.017 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr6_+_44195008 0.017 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr1_-_92951593 0.017 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr2_-_133539627 0.017 NCKAP5
NCK-associated protein 5
chrX_+_153770458 0.016 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr2_-_89513056 0.016 IGKC
immunoglobulin kappa constant
chr13_-_27334777 0.016 NM_005288
GPR12
G protein-coupled receptor 12
chr20_+_46130600 0.015 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr3_+_195447810 0.015 MUC20
mucin 20, cell surface associated
chr11_+_11863520 0.015 USP47
ubiquitin specific peptidase 47
chr22_-_44893179 0.015 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr17_-_1090562 0.015 NM_001159746
ABR
active BCR-related gene
chr15_+_57511616 0.015 NM_207040
TCF12
transcription factor 12
chr13_-_39564857 0.015 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr22_+_31489343 0.015 SMTN
smoothelin
chr17_+_39388714 0.015 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr7_-_99527242 0.014 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr9_+_131683173 0.014 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr2_-_234474197 0.014 NM_018218
USP40
ubiquitin specific peptidase 40
chr12_-_103311380 0.014 NM_000277
PAH
phenylalanine hydroxylase
chr8_-_133772808 0.013 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr10_+_118350470 0.013 NM_006229
PNLIPRP1
pancreatic lipase-related protein 1
chr8_-_37707430 0.013 NM_018310
BRF2
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
chr1_-_153919140 0.013 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr6_-_11382501 0.013 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr7_-_97881436 0.013 NM_015395
TECPR1
tectonin beta-propeller repeat containing 1
chrX_-_19817907 0.013 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr18_+_32335939 0.012 NM_001390
NM_001391
DTNA

dystrobrevin, alpha

chr19_-_48547180 0.012 NM_019855
CABP5
calcium binding protein 5
chr2_-_136288768 0.012 NM_032143
ZRANB3
zinc finger, RAN-binding domain containing 3
chr12_-_123187842 0.012 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr9_-_19033183 0.012 NM_153707
FAM154A
family with sequence similarity 154, member A
chr14_+_39734475 0.012 NM_203354
CTAGE5
CTAGE family, member 5
chr9_-_100707102 0.012 NM_018437
HEMGN
hemogen
chr12_-_2944149 0.012 NM_031474
NRIP2
nuclear receptor interacting protein 2
chr10_+_7745325 0.011 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_55277421 0.011 RTN4
reticulon 4
chrX_-_110513750 0.011 NM_014289
CAPN6
calpain 6
chr6_-_163148800 0.011 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr3_-_128186090 0.011 NM_153330
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr3_-_97754147 0.011 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chrX_-_52683949 0.011 NM_173358
SSX7
synovial sarcoma, X breakpoint 7
chr19_-_46285746 0.010 DMPK
dystrophia myotonica-protein kinase

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.